Murari Kumar started his acting career with ACT One theatre group in Delhi. He has acted in various hindi films in last 15 years of which the most notable is his character Guddu in Gangs of Wasseypur part 2 and Peddler which screened in Cannes 2012.

He has mainly been associated with Anurag Kashyap.

He is also one of voice in Radio City's Babbar Sher