Kelly Karbacz played the part of Judy in the 2008 comedy Get Smart starring Steve Carell.

She also appeared in the 2003 film A Tale of Two Pizzas as well as American TV shows such as Regular Joe, Undeclared, Law & Order, Law & Order: Special Victims Unit, Law & Order: Criminal Intent, Without a Trace and Third Watch.

She is also a theatre actress. In 2012, Karbacz played the role of Casey in the Seattle production of First Date the Musical.

In 2016, Karbacz joined the cast of Orange Is The New Black in their fourth season, playing the role of Kasey Sankey, an inmate with white supremacist beliefs.