Jesse Wigutow (born May 25, 1973) is an American screenwriter and producer. He was raised in New York City, where he grew up before pursuing higher education. He attended Cornell University, earning a BA in English. During that time, he wrote and performed plays at the Cornell Theater Arts program.

Wigutow’s work spans both film and television. He wrote the screenplay for It Runs in the Family (2003), directed by Fred Schepisi and wrote Disney's Tron: Ares (2025). In television, he is credited for writing episodes 4 and 8 of Marvel Studios' Daredevil: Born Again (2025-), and also serves as an consulting producer and co-executive producer on Season 1 and Season 2 respectively.

He worked on unproduced remake of The Crow and The Osterman Weekend.